Name | S-acetylthioglycolic acid N-*hydroxysuccinimide E |
Synonyms | SATA SUCCINIMIDYL ACETYLTHIOACETATE N-SUCCINIMIDYL (ACETYLTHIO)ACETATE S-ACETYLTHIOGLYCOLIC ACID NHS ESTER n-hydroxysuccinimides-acetylthioacetate S-ACETYLTHIOGLYCOLIC ACID N-SUCCINIMIDYL ESTER S-acetylthioglycolic acid N-*hydroxysuccinimide E S-ACETYLTHIOACETIC ACID-N-HYDROXYSUCCINIMIDE ESTER S-ACETYLTHIOGLYCOLIC ACID N-HYDROXYSUCCINIMIDE ESTER |
CAS | 76931-93-6 |
EINECS | 678-479-6 |
InChI | InChI=1/C8H9NO5S/c1-5(10)15-4-8(13)14-9-6(11)2-3-7(9)12/h2-4H2,1H3 |
Molecular Formula | C8H9NO5S |
Molar Mass | 231.23 |
Density | 1.46±0.1 g/cm3(Predicted) |
Melting Point | 84-89°C |
Boling Point | 337.3±44.0 °C(Predicted) |
Flash Point | 157.8°C |
Solubility | acetonitrile: 50mg/mL |
Vapor Presure | 0.000106mmHg at 25°C |
Appearance | powder |
Color | White to Off-White |
BRN | 7815491 |
Storage Condition | -20°C |
Stability | Moisture Sensitive |
Refractive Index | 1.561 |
MDL | MFCD00036891 |
WGK Germany | 3 |
FLUKA BRAND F CODES | 3-10-23 |
HS Code | 29309090 |
biological activity | N-Succinimidyl S-acetylthioacetate (SATA), a protein modifying agent that introduces a thiol group into a protein molecule. N-Succinimidyl S-acetylthioacetate thiol groups are added to proteins and other amine-containing molecules in a protected form. |
Use | a thiolating reagent for primary amines; The thiol can be deprotected under mild conditions. The coupling reaction is typically initiated at a pH of 7.5 to form a primary amine-containing molecule through an amide bond. Deprotection can occur with 0.05m hydroxylamine at neutral pH. For the preparation of conjugates of enzyme immunocrosslinkers and hapten carrier molecules. |